著書:色素細胞 (共著)慶應義塾大学出版会 (’01)色素異常症の動物モデルとしての鳥類色素変種
新・生物学 (慶應義塾大学生物学教室 編)(共著)(’96)人の体の中でエネルギーはどのように作られ使われて行くか?
研究論文:
Matsumoto J., Wada K. and Akiyama T. Neural crest cell differentiation
and carcinogenesis: capability of goldfish erythrophoroma cells for multiple
differentiation and clonal polymorphism in their melanogenic variants.
Journal of Investigative Dermatology, 92: 255s-260s (1989)
Akiyama T., Matsumoto J. and Hirai S. Myosin and actin in melanophore-like
variants of goldfish erythrophoroma cells: their intra-cellular distribution
and possible association with pigment translocation. Cell Tissue Research,
259;239-246 (1990)
Matsumoto J., Akiyama T., Hirose E., Nakamura M., Yamamoto H. and Takeuchi
T. The expression of the melanogenic phenotype in the orange-colored mutant
of medaka fish introduced with mouse tyrosinase gene. Zoological Science,
8: 1081 (1991)
Matsumoto J., Akiyama T., Nemoto N., Prince Masahito and Ishikawa T. Appearance
of tumorous phenotypes in goldfish erythrophores transfected with ras,
src, and myc oncogenes and spontaneous differentiation of the transformants
in vitro. Journal of Investigative Dermatology, 100: 214s-221s
(1993).
秋山豊子 アルビノ・ニワトリ細胞に遺伝子導入されたマウス・チロシナーゼはどう働くか?I.
遺伝子導入のためのベクターウイルスの構築 秋山豊子慶應義塾大学日吉紀要 自然科学
15: 1-15(1994)
秋山豊子 アルビノ・ニワトリ細胞に遺伝子導入されたマウス・チロシナーゼはどう働くか? II. プロウイルスのトランスフェクションとレトロウイルス産生 慶應義塾大学 日吉紀要 自然科学 16:1-11 (1994)
Akiyama T., Whitaker B., Federspiel M. Hughes S. H., Yamamoto H., Takeuchi
T. and Brumbaugh J. Tissue-specific expression of mouse tyrosinase gene
in cultures chicken cells. Experimental Cell Research, 214: 154-162 (1994)
Akiyama T. and Nakamura M. Effects of growth factors on melanocyte proliferation
and differentiation of black silkie chicken. Zoological Science 12 suppl.:
65 (1995)
Akiyama T. and Nakamura M. Melanocytes in black silkie chicken migrate
through the dorsoventral route and differentiation is stimulated by insulin-like
growth factors. Melanoma Research 5 suppl. 2:41.(1995)
Akiyama T. Effects of stem cell factor on melanocyte proliferation and
differentiation of black silkie chicken. Zoological Science,13suppl.:75
(1996)
Hirose Y., Yoshida T., Akiyama T. and Iwanami Y. Pigments and intracellular
structure of pigment cells in Botrylloides simodensis (Ascidiacea, urochordata).
Pigment Cell Research, 9 suppl. 5: 218(1996)
秋山豊子 アルビノ・ニワトリ細胞に遺伝子導入されたマウス・チロシナーゼ遺伝子はどう働くか?III. in
vitroとin vivo におけるウイルス感染とその遺伝子発現の検定 慶應義塾大学 日吉紀要自然科学 21:1-14
(1997)
Tobita T., Akiyama T., Tsubokawa T. and Kino K. Preparation of melanocytes
proliferation differentiation and survival promoting fractions from Buffalo
rat liver cell-conditioned medium. Zoological Science 14 suppl. 80 (1997)
Hirose Y., Yoshida T., Akiyama T., Ito S. and Iwanami Y. Pigment cell representing
polychromatic colony color in Botrylloides simodensis (Ascidiacea, urochordata):
Cell morphology and pigment substances. Zoological Science 15: 489-497
(1998)
Tobita T., Akiyama T., Kino, K. Isolation of two factors that stimulate
proliferation and differentiation of melanocytes in buffalo rat liver cell-conditioned
medium Zoological Science 15, suppl.: 66 (1998)
Tobita, T., Akiyama, T., Kino,K. Proliferation and differentiation stimulating
factors of melanocytes in black silkie chicken in vitro. Pigment Cell Res.,
11 (6): 395 (1998)
Tobita,T., Akiyama,T. et al. Autosomal albino chicken mutation (ca/ca)
deletes six nucleotide at a copper binding site of the Tyrosinase gene.
Pigment Cell Res., suppl. 7:80 (1999)
Akiyama T.,Tobita,T. Endothelins induced proliferation and differentiation
of melanocytes in black silky chickens via endothelin receptor B2. Pigment
Cell Res., 7:80 (1999)
Tobita T., Akiyama T.,et al. Autosomal albino chicken mutation (ca/ca)
deletes hexanucleotide (GACTGC817) at a copper binding site of the tyrosinase
gene. Poultry Sci., 79:46-50 (2000)
Tobita T. T., Akiyama T. Endothelin receptor cDNA cloning from melanophores
of medaka fish, Oryzias Latipes. Pigment Cell Research 13, (3):199 (2000)
Akiyama T., Kurabayashi A.. and Tobita-teramoto T., Analysis of endothelin
receptor expression in medaka fish pigment cells using the specific antibodies.Pigment
Cell Res., 13: 413 (2000)
Kurabayashi A., Tobita-Teramoto T. and Akiyama T., Studies on chicken albinism:
A recessive white (c/c) albino may be caused by low level expression of
tyrosinase gene.Zoological Science (2001)(in press)
Akiyama T., Nakamura M., Kitamura K. and Hirose E.., Behavior and ultreafinestructure
of dermal melanocytes in black silky chicken in vivo and in vitro. Zoologocqal
Scoence (2001)(in press)
学会発表 (作成中)